Why was the shingles vaccine recalled?

The company issued the voluntary recall early last year after one customer reported an empty antigen vial and another customer said there was an “abnormal appearance of the antigen powder in a vial,” a GSK spokesperson told Fierce Pharma.


Why was Shingrix recalled?

The recall is a precautionary measure due to the potential for loss of integrity of the antigen vial, although a search of GSK's global adverse event database has not identified a safety signal for Shingrix lot #9LH3Y related to infections or lack of efficacy, events that could occur if there were a loss of integrity ...

Is there a lawsuit against the shingles vaccine?

August 18, 2021 Update: The shingles vaccine lawsuit in the MDL was originally filed on behalf of 22 plaintiffs. In August 2021, it is now over 2130. The first Zostavax trial will be on January 18, 2022. The outcome of this trial will have an impact on the ultimate settlement compensation payouts in these lawsuits.


Is the latest shingles vaccine safe?

Shingrix is more than 90% effective at preventing shingles and long-term nerve pain. You may experience some short-term side effects because Shingrix causes a strong response in your immune system. After getting Shingrix: Most people had a sore arm.

What are the chances of getting Guillain Barré from the shingles vaccine?

A self-controlled case series found an increased risk of GBS during a 42-day period after vaccination with Shingrix [11]. The study also found an estimated three cases of GBS per million vaccinations administered in adults aged 65 and older [11].


Expert Insights: Should I get the shingles vaccine?



Is there a downside to the shingles vaccine?

Most people got a sore arm with mild or moderate pain after getting Shingrix, and some also had redness and swelling where they got the shot. Some people felt tired, had muscle pain, a headache, shivering, fever, stomach pain, or nausea.

How many people get sick from shingles vaccine?

Like all vaccines, the shingles vaccines (Zostavax and Shingrix) can cause side effects, but they're generally mild and do not last long. Common side effects that occur in at least 1 in 10 people are: headache. redness, pain, swelling, itching and warmth at the injection site.

Why do some doctors not recommend the shingles vaccine?

A live virus vaccine has the potential of causing virus shedding, infection and transmission. In other words, it can actually cause shingles. Some side-effects might be categorized as minor including pain, swelling and redness at the injection site.


Do I really need the new shingles vaccine?

Shingrix provides strong protection against shingles and long-term pain from the disease. Two doses of Shingrix are more than 90% effective at preventing shingles. So it's very important that you get this vaccine.

Can Shingrix cause Guillain Barre Syndrome?

The primary analysis (claims-based, all doses) found an increased risk of GBS during the 42 days following vaccination with Shingrix, with an estimated 3 excess cases of GBS per million doses administered to adults aged 65 years or older.

Can Shingrix cause neurological problems?

In 2021, the FDA issued a new warning about a possible association between the Shingrix vaccine and a very rare neuro autoimmune disorder called Guillain-Barre syndrome (GBS). 5 GBS is a condition involving damage to peripheral nerves.


Can shingles vaccine trigger autoimmune disease?

Our study showed no significantly increased risks of severe autoimmune adverse events, except arthritis and alopecia, after vaccination. Compared to the unexposed, patients with zoster vaccination had 2.2 and 2.7 times the odds of developing arthritis and alopecia, respectively (P<0.001 and P=0.015, respectively).

How many years does a shingles vaccine last?

The shingles vaccine provides strong protection from shingles and PNH for approximately 7 years . People should aim to get the vaccine if they are aged 50 years or above with a healthy immune system or 19 years and above with a weakened immune system.

What triggers shingles?

Causes of shingles

Shingles is caused by the reactivation of the varicella-zoster virus, which is the virus that causes chickenpox. After you have had chickenpox, the varicella-zoster virus lies dormant (inactive) inside your body. It can become reactivated at a later stage and cause shingles.


How is the new shingles vaccine different from the old one?

Unlike the other vaccine that's been available for shingles since 2006, called Zostavax, this new vaccine is inactivated. That means it does not contain a live virus. Because of that, it is safe in people who have weakened immune systems.

Is the second shingles vaccine worse?

Shingrix is administered in two doses, usually two to six months apart. Shingrix is safe and effective for most people. Side effects from the second dose of Shingrix are somewhat more common than the first dose, although that's not always the case. Most side effects of Shingrix are mild and resolve on their own.

When do side effects of shingles vaccine kick in?

The shingles vaccine is given in a two-shot series. You may experience side effects after the first, second, or both shots. Most of the time, these symptoms are mild and occur immediately following vaccination. They typically only last for two or three days.


Can the shingles vaccine cause heart palpitations?

Severe allergic reactions to Shingrix are very rare. Signs of a severe allergic reaction can include hives, swelling of the face and throat, difficulty breathing, a fast heartbeat, dizziness, and weakness. These would start a few minutes to a few hours after the vaccination.

How many times can you get shingles?

Most people who develop shingles have only one episode during their lifetime. However, you can have shingles more than once. If you have shingles, direct contact with the fluid from your rash blisters can spread VZV to people who have never had chickenpox or never received the chickenpox vaccine.

What happens if you don't get 2nd shingles vaccine?

If you received one dose of the Shingrix® vaccine but a shortage kept you from getting your second dose – a painful case of shingles still could be in your future. The makers of Shingrix claim its protection is sustained at a high level for at least four years – but only if you get both doses two to six months apart.


Should I get shingles vaccine if I never had chickenpox?

Who Should Get Zostavax? People 60 years of age or older should get shingles vaccine (Zostavax). They should get the vaccine whether or not they recall having had chickenpox, which is caused by the same virus as shingles.

Who Cannot have live shingles vaccine?

People with a weakened immune system cannot have live vaccines. They will be offered a non-live vaccine called Shingrix. It activates the immune system but also contains an ingredient called an adjuvant, which helps to boost the response to the vaccine.

Can Shingrix cause stroke?

Researchers found: Receiving the shingles vaccine lowered the risk of stroke by about 16%, lowered the risk of ischemic (clot-caused) stroke by about 18% and lowered the risk of hemorrhagic (bleeding) stroke by about 12%;


Can you get Bell's palsy from shingles vaccine?

Shingles vaccines have been used in several countries, including the US and Canada. Previous studies have found that Zostavax is safe and well-tolerated. There have been a few cases of Bell's Palsy and Guillain- Barre Syndrome (GBS) reported to the MHRA following exposure to the vaccine.

Can the shingles vaccine cause paralysis?

Federal drug regulators have announced new warnings about the potential risk of Guillain-Barre Syndrome after a shingles vaccine, indicating side effects of Shingrix may cause the rare and serious disorder, which leaves users with muscle weakness and even paralysis.