What is the most common cause of hypomagnesemia?

Hypomagnesemia usually happens due to one of the following:
Too little intake of magnesium into your body. Excessive loss of magnesium through your kidneys (pee) or your gastrointestinal tract (stool).


What diseases cause low magnesium?

Magnesium deficiency in healthy people is rare but it can be caused by:
  • a poor diet (especially in elderly people or those who don't have enough to eat)
  • type 2 diabetes.
  • digestive problems such as Crohn's disease.
  • long-term vomiting or diarrhoea.
  • kidney problems.
  • long-term use of diuretics.


What happens when you have hypomagnesemia?

Symptoms include anorexia, nausea, vomiting, lethargy, weakness, personality change, tetany (eg, positive Trousseau or Chvostek sign, spontaneous carpopedal spasm, hyperreflexia), tremor, and muscle fasciculations.


What are three symptoms of hypomagnesemia?

Symptoms of hypomagnesemia include:
  • Nausea and/or vomiting.
  • Weakness and sleepiness.
  • Personality changes.
  • Muscle spasms or tremors.
  • Loss of appetite.


Which people have a high risk of hypomagnesemia and why?

Conditions that increase the risk of magnesium deficiency include gastrointestinal (GI) diseases, advanced age, type 2 diabetes, use of loop diuretics (such as Lasix), treatment with certain chemotherapies, and alcohol dependence.


Hypomagnesemia: Causes



Is there a cure for hypomagnesemia?

Know that hypomagnesemia is treatable and that symptoms usually go away once your magnesium levels are back to normal with treatment.

Does hypomagnesemia affect the heart?

Patients with acute myocardial infarction who have mild hypomagnesemia appear to have a two- to threefold increase in the frequency of ventricular arrhythmias in the first 24 hours when compared with those with normal plasma magnesium levels [6,7].

What medications can cause hypomagnesemia?

Hypomagnesemia occurs with both loop diuretics (furosemide, bumetanide, torsemide, and ethacrynic acid) and thiazide diuretics (chlorothiazide, hydrochlorothiazide, indapamide, and metolazone).


What medications deplete magnesium?

Prescribed drugs further deplete the stores of magnesium in the body. Among these are proton pump inhibitors for acid reflux, including Prilosec, Zantac or Nexium; statins; and blood pressure medications, Dean said. The biggest magnesium busters are drugs containing fluoride, she said.

How do you fix magnesium deficiency?

People wanting to increase their magnesium levels by improving absorption could try:
  1. reducing or avoiding calcium-rich foods two hours before or after eating magnesium-rich foods.
  2. avoiding high-dose zinc supplements.
  3. treating vitamin D deficiency.
  4. eating raw vegetables instead of cooking them.
  5. quitting smoking.


How serious is a magnesium deficiency?

Severe magnesium deficiency can cause problems with the function of your nervous system and heart. It can lead to things like muscle spasms, seizures, or heart arrhythmias. Oral or intravenous magnesium can supplement a low magnesium level. But it's important to find and address the underlying cause.


What foods to avoid if you have hypomagnesemia?

You will need to limit all foods that have magnesium. These include: Dark green, leafy vegetables, including salad greens, spinach, collards, kale, and chard. All nuts and nut products, including peanuts, almonds, walnuts, pecans, cashews, brazil nuts, macadamia nuts, peanut butter, and almond butter.

Is hypomagnesemia life threatening?

Hypomagnesemia can potentially cause fatal complications including ventricular arrhythmia, coronary artery spasm, and sudden death. It also associates with increased mortality and prolonged hospitalization [6, 7].

What does low magnesium feel like?

Twitches, tremors, and muscle cramps are signs of magnesium deficiency. In worst-case scenarios, deficiency may even cause seizures or convulsions ( 1 , 3 ). Scientists believe these symptoms are caused by a greater flow of calcium into nerve cells, which overexcites or hyperstimulates the muscle nerves (4).


What fruit is highest in magnesium?

Fruits high in magnesium include dried figs, avocados, guavas, bananas, kiwi fruit, papayas, blackberries, raspberries, cantaloupes, and grapefruit. The daily value (DV) for magnesium 420mg per day.

What cancers cause low magnesium?

Patients with colorectal cancer had the highest risk of grade 3/4 hypomagnesemia events among patients with cancer: compared with chemotherapy alone, the addition of cetuximab increased the risk of grade-3/4 hypomagnesemia with RRs of 7.14 (95% CI, 3.13 to 16.27; P<0.001), whereas patients receiving panitumumab were ...

What organs are affected by magnesium?

Every organ in the body, especially the heart, muscles, and kidneys, needs the mineral magnesium. It also contributes to the makeup of teeth and bones. Magnesium is needed for many functions in the body. This includes the physical and chemical processes in the body that convert or use energy (metabolism).


Can vitamin D deplete magnesium?

Mg is essential in the metabolism of vitamin D, and taking large doses of vitamin D can induce severe depletion of Mg. Adequate magnesium supplementation should be considered as an important aspect of vitamin D therapy.

How long does it take to restore magnesium levels?

Chronic magnesium deficiency is often associated with normal serum magnesium despite deficiency in cells and in bone; the response to oral supplementation is slow and may take up to 40 weeks to reach a steady state.

Can stress cause hypomagnesemia?

Mild hypomagnesemia can be observed in response to mid- or long-term exposure to stress.


Which patient is at a higher risk of hypomagnesemia?

Medical conditions putting persons at high risk for hypomagnesemia are alcoholism, congestive heart failure, diabetes, chronic diarrhea, hypokalemia, hypocalcemia, and malnutrition (strength of recommendation: C, based on expert opinion, physiology, and case series).

Which among patient is at most risk for hypomagnesemia?

Which patient is at most risk for hypomagnesemia? The answer is A. The correct answer is a 55 year old who is a chronic alcoholic. Patients who suffer from alcoholism have an increased secretion of magnesium and usually do not eat a proper diet, therefore, they are at risk for lower magnesium levels.

Can hypomagnesemia reversed?

For the most part, the signs and symptoms of hypomagnesemia are reversible with magnesium replacement. Therapy can be oral for patients with mild symptoms or intravenous for patients with severe symptoms or those unable to tolerate oral administration.


What does hypomagnesemia do to muscles?

Hypomagnesemia does not always cause symptoms, but some early ones can include muscle twitching, numbness, and tingling. Without treatment, hypomagnesemia can cause health problems and reduce the body's calcium and potassium levels.

Can you be hospitalized for low magnesium?

Brief Summary: Hypomagnesemia is a common entity in the inpatient and outpatient setting. in previous retrospective study hypomagnesemic patients have higher mortality and longer hospitalization.